DR. JENNIFER MITCHEL
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First-authored Publications

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Mitchel JA, Das A, O’Sullivan MJ, Stancil I, Koehler S, Nieto MA, Fredberg JJ, Butler JP, Bi D, Park J-A. In Airway Epithelial cells, the Unjamming Transition is Distinct from the Epithelial-to-Mesenchymal Transition. Nature Communications 2020, Oct 7. 
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O’Sullivan MJ*, Mitchel JA*, Mwase C, McGill M, Kanki P, Park J-A. In well-differentiated human bronchial epithelial cells, TGF-β induces expression of Furin. Am J Physiol Lung Cell Mol Physiol. 2021 Feb 1;320(2):L246-L253. Epub 2020 Nov 11. (*Equal Contribution)
[pdf] [pubmed]

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Lan B*, Mitchel JA*, O’Sullivan MJ, Park CY, Kim JH, Cole WC, Butler JP, Park J-A. Airway epithelial compression promotes airway smooth muscle proliferation and contraction. AJP Lung Cellular and Molecular Physiology 2018 Nov 1;315(5):L645-L652. (*Equal contribution)
[pdf] [pubmed]

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Mitchel JA, Antoniak S, Lee JH, Kim SH, McGill M, Kasahara DI, Randell SH, Israel E, Shore SA, Mackman N, Park J-A. IL-13 Augments Compressive Stress-Induced Tissue Factor Expression in Human Airway Epithelial Cells. American Journal of Respiratory Cell and Molecular Biology 2016 Apr; 54:524-31.
[pdf] [pubmed]

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Mitchel JA, Martin IS, Hoffman-Kim D. Neurient: an algorithm for automatic tracing of confluent neuronal images to determine alignment. Journal of Neuroscience Methods. 2013 Apr; 214:210-22.
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Mitchel JA, Hoffman-Kim D. Cellular Scale Anisotropic Topography Guides Schwann Cell Motility. PLoS ONE 2011 Sept; 6(9): e24316
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Contributing-author Publications

​DeCamp SJ, Tsuda V, Ferruzzi J, Koehler SA, Giblin JT, Roblyer D, Zaman MH, Ogassavara NC, Mitchel JA, Butler JP, Fredberg JJ. Epithelial layer unjamming shifts energy metabolism toward glycolysis.  Scientific Reports 2020.

O’Sullivan MJ, Mitchel JA, Das A Koehler S, Levine H, Bi D, Nagel ZD, Park J-A. Irradiation induces epithelial cell unjamming. Frontiers in Cell and Developmental Biology, 2020 Feb 22.
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Kılıç A, Ameli A, Park J-A, Koh A, Tantisira K, Santolini M, Cheng F, Mitchel JA, McGill M, O’Sullivan MJ, De Marizo M, Sharma A, Randell SH, Drazen JM, Fredberg JJ, Weiss ST. Mechanical forces induce an asthma gene signature in healthy airway epithelial cells. Scientific Reports, 2020 Jan 22.

Kim SH, Mitchel JA, McGill M, Cremona T, Tan LH, Kasahara D, Anathy V, Israel E, Park J-A. Mechanical compression induces maspin secretion from well-differentiated bronchial epithelial cells. Journal of Allergy and Clinical Immunology, 2019.

He S, Carman CV, Lee JH, Lan B, Koehler S, Atia L, Park CY, Kim JH, Mitchel JA, Park J-A, Butler JP, Lu Q, Fredberg JJ. The tumor suppressor p53 can promote collective cellular migration. PLoS One. February 1, 2019. 

Barrios J, Kho A, Aven L, Mitchel JA, Park J-A, Randell SH, Miller LA, Tantisira K, Ai X. Pulmonary neuroendocrine cells provide GABA for goblet cell hyperplasia in primate models. American Journal of Respiratory Cell and Molecular Biology. 2018 Dec 20 

Glass K, Thibault D, Guo F, Mitchel JA, Pham B, Qiu W, Li Y, Jiang S, Castaldi P, Silverman EK, Raby B, Park J-A, Yuan GC, Zhou X. Integrative epigenomic analysis in differentiated human primary bronchial epithelial cells exposed to cigarette smoke. Scientific Reports, 2018.

Panganiban RA, Sun M, Dahlin A, Park H-R, Kan M, Himes BE, Mitchel JA, Iribarren C, Jorgenson E, Randell SH, Israel E, Tantisira K, Shore S, Park J-A, Weiss ST, Wu AC, Lu Q. A functional splice variant associated with decreased asthma risk abolishes the ability of gasdermin B to induce epithelial cell pyroptosis. Journal of Allergy and Clinical Immunology. 2018 Jan. 

Atia L, Bi D, Sharma Y, Mitchel JA, Gweon B, Koehler S, DeCamp SJ, Lan B, Hirsch R, Pegoraro AF, Lee KH, Starr J, Weitz DA, Martin AC, Park J-A, Butler JP, Fredberg JF. Geometrical constrains during epithelial jamming. Nature Physics. 2018 Apr;14: 613–620

Park J-A, Kim JH, Bi D, Mitchel JA, Qazvini NT, Tantisira K, Park CY, McGill M, Kim SH, Gweon B, Notbohm J, Steward R Jr, Burger S, Randell SH, Kho AT, Tambe DT, Hardin C, Shore SA, Israel E, Weitz DA, Tschumperlin DJ, Henske EP, Weiss ST, Manning ML, Butler JP, Drazen JM, Fredberg JJ. Unjamming and cell shape in the asthmatic airway epithelium. Nature Materials 2015 Oct; 14:1040-8 

López-Fagundo C, Mitchel JA, Ramchal TD, Dingle YT, Hoffman-Kim D. Navigating neurites utilize cellular topography of Schwann cell somas and processes for optimal guidance. Acta Biomaterialia. 2013 July; 9:7158-68.
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Kofron CM, Liu YT, López-Fagundo CY, Mitchel JA, Hoffman-Kim D. Neurite outgrowth at the biomimetic interface. Annals of Biomedical Engineering 2010 June; 38(6):2210-25
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